BY ORDER OF THE
SECRETARY OF THE AIR FORCE
DEPARTMENT OF THE AIR FORCE
MANUAL 91-110
24 FEBRUARY 2022
Safety
NUCLEAR SAFETY REVIEW AND
LAUNCH APPROVAL FOR SPACE OR
MISSILE USE OF RADIOACTIVE
MATERIAL
COMPLIANCE WITH THIS PUBLICATION IS MANDATORY
ACCESSIBILITY: Publications and forms are available on the e-Publishing website at
www.e-publishing.af.mil for downloading or ordering.
RELEASABILITY: There are no releasability restrictions on this publication.
OPR: HQ AF/SEC Certified by: AFSEC/CV
(Col Lawrence A. Nixon)
Supersedes: AFMAN 91-110, 22 May 2019 Pages: 49
This Department of the Air Force Manual (DAFMAN) implements Air Force Policy Directive
(AFPD) 91-1, Nuclear Weapons and Systems Surety, and establishes the nuclear safety review and
launch approval procedures for radioactive materials intended for space or missiles use. This
DAFMAN is consistent with the policy established in National Security Presidential Memorandum
#20 (NSPM-20), Launch of Spacecraft Containing Space Nuclear Systems; Space Policy
Directive-6 (SPD-6), Memorandum on the National Strategy for Space Nuclear Power and
Propulsion; Department of Defense Directive (DoDD) 3200.11, Major Range and Test Facility
Base; Department of Defense Instruction (DoDI) 3100.12, Space Support; DoDD 3100.10 Space
Policy. In addition, this DAFMAN invokes the applicable guidance and procedures found in Air
Force Manual (AFMAN) 48-148, Ionizing Radiation Protection, and AFMAN 40-201,
Radioactive Materials (RAM) Management. This manual applies to all Regular Air Force, United
States Space Force, Air Force Reserve, Air National Guard, Department of the Air Force civilian
personnel, and contractors, if included in the applicable contract units that design, develop, modify,
evaluate, test, and/or operate existing and future Department of the Air Force (DAF) space systems
(operational, test, and experimental), DAF space support systems, and to organizations who use or
operate DAF launch facilities or ranges. Compliance with Attachments 2 and 3 is mandatory.
Compliance with Attachments 4 and 5 is not mandatory. Ensure all records generated as a result
of processes prescribed in this publication adhere to Air Force Instruction (AFI) 33-322, Records
Management and Information Governance Program, and are disposed in accordance with the Air
Force Records Disposition Schedule, which is located in the Air Force Records Information
