BY ORDER OF THE
SECRETARY OF THE AIR FORCE
AIR FORCE INSTRUCTION 48-101
8 DECEMBER 2014
Aerospace Medicine
AEROSPACE MEDICINE ENTERPRISE
COMPLIANCE WITH THIS PUBLICATION IS MANDATORY
Publications and forms are available on the e-Publishing website at
www.e-Publishing.af.mil for downloading or ordering.
There are no releasability restrictions on this publication.
OPR: AF/SG3P
Supersedes: AFI48-101, 19 October 2011
Certified by: AF/SG3/5
(Maj Gen Dorothy A. Hogg)
Pages: 37
This instruction implements AFPD 48-1, Aerospace Medicine Enterprise. It provides guidance
and establishes procedures for conducting the multidisciplinary aspects of the Aerospace
Medicine Enterprise (AME). It describes the key Aerospace Medicine programs in support of
the operational aerospace mission and links them to the desired operational effects: Promote and
Sustain a Healthy and Fit Force, Prevent Illness and Injury, Restore Health, and Sustain Human
Performance. This publication serves as a program management outline for the AME and the
seven subordinate programs. It provides a strategic overview of the objectives, desired effects,
metrics and reporting requirements for the programs which constitute the AME. Tactical
management of the subordinate programs is referenced in the appropriate publications.
This instruction addresses the requirement for development of Team Aerospace. This instruction
interfaces with Air Force 10-, 11-, 36-, 40-, 41-, 48-, 60-, 61-, 62-, 63, and 90 series publications.
This publication applies to the regular Air Force and the Air Reserve Components. The
authorities to waive wing/unit level requirements in this publication are identified with a Tier
(“T-0, T-1, T-2, T-3”) number following the compliance statement. See AFI 33-360,
Publications and Forms Management, for a description of the authorities associated with the Tier
numbers. Requests for waivers must be submitted through the chain of command to the
appropriate Tier waiver approval authority, or, alternately, to the Publication OPR for non-tiered
compliance items. Any organizational level may supplement this instruction. Refer
recommended changes and questions about this publication to the Office of Primary
Responsibility (OPR) using AF Forms 847, Recommendation for Change of Publication; route
AF Form 847 from the field through the appropriate chain of command. Ensure that all records
created as a result of processes prescribed in this publication are maintained in accordance with
Certified Current, 22 APRIL 2020