BY ORDER OF THE
SECRETARY OF THE AIR FORCE
DEPARTMENT OF THE AIR FORCE
INSTRUCTION 48-107 VOLUME 2
24 NOVEMBER 2020
Aerospace Medicine
EN ROUTE CRITICAL CARE
COMPLIANCE WITH THIS PUBLICATION IS MANDATORY
ACCESSIBILITY: Publications and forms are available on the e-Publishing website at
www.e-Publishing.af.mil for downloading or ordering.
RELEASABILITY: There are no releasability restrictions on this publication.
OPR: AMC/SGK
Supersedes: AFI48-307V2, 10 January 2017
Certified by: AMC/SG
(Brig Gen West)
Pages: 59
This instruction implements Department of Air Force Policy Directive (DAFPD) 48-1,
Aerospace and Operational Medicine Enterprise, and is consistent with DAFPD 10-29,
Worldwide Aeromedical Evacuation Operations, by establishing administrative and operational
responsibilities and procedures for aeromedical transport of critically ill or injured patients. This
instruction provides guidance for management, qualification, training, operations, and logistic
sustainment activities in support of air transport of critically ill or injured patients across the
range of military operations. This publication applies to all military and civilian personnel of the
Regular Air Force, Air Force Reserve, and Air National Guard. This publication does not apply
to the United States Space Force. This publication requires the collection and or maintenance of
information protected by the Privacy Act of 1974 authorized by Title 10 United States Code
Section (U.S.C.) 9013, Secretary of the Air Force, and Executive Order 9397 (SSN), as
amended. The applicable System of Records Notice, F036 AF PC C, Military Personnel Records
System, is available at: https://dpcld.defense.gov/privacy/SORNS.aspx. Ensure all records
generated as a result of processes prescribed in this publication adhere to Air Force Instruction
(AFI) 33-322, Records Management and Information Governance Program, and are disposed in
accordance with the Air Force Records Disposition Schedule, which is located in the Air Force
Records Information Management System. Refer recommended changes and questions about this
publication to the Office of Primary Responsibility (OPR) using AF Form 847, Recommendation
for Change of Publication; route the AF Form 847 through the appropriate chain of command
and parent major command (MAJCOM). This publication may be supplemented at any level, but
all direct supplements must be routed to the OPR of this publication for coordination prior to
certification and approval. The authorities to waive wing/unit level requirements in this
publication are identified with a Tier (“T-0, T-1, T-2, T-3”) number following the compliance
